MARC details
| 000 -LEADER |
|---|
| fixed length control field |
03005cam a22003014a 4500 |
| 001 - CONTROL NUMBER |
|---|
| control field |
48399138 |
| 003 - CONTROL NUMBER IDENTIFIER |
|---|
| control field |
OCoLC |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20200706162429.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
011107s2003 maum b a001 0 eng |
| 010 ## - LIBRARY OF CONGRESS CONTROL NUMBER |
|---|
| LC control number |
2001056298 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
026213411X |
| 042 ## - AUTHENTICATION CODE |
|---|
| Authentication code |
pcc |
| 050 00 - LIBRARY OF CONGRESS CALL NUMBER |
|---|
| Classification number |
QH 430 |
| Item number |
.M855 2003 |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Moss, Lenny. |
| 9 (RLIN) |
32051 |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
What genes can't do |
| Statement of responsibility, etc |
Lenny Moss. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
|---|
| Place of publication, distribution, etc |
Cambridge, MA : |
| Name of publisher, distributor, etc |
MIT Press, |
| Date of publication, distribution, etc |
2003. |
| 264 ## - PUBLISHER--PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
|---|
| Place of publication, distribution, etc |
Cambridge, MA : |
| Name of publisher, distributor, etc |
MIT Press, |
| Date of publication, distribution, etc |
2003. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
xx, 228 pages : |
| Other physical details |
illustrations ; |
| Dimensions |
23 cm. |
| 490 1# - SERIES STATEMENT |
|---|
| Series statement |
Basic bioethics. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
|---|
| Bibliography, etc |
Includes bibliographical references (p. [205]-215) and index. |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
1. Genesis of the Gene -- 2. The Rhetoric of Life and the Life of Rhetoric -- 3. A Critique of Pure (Genetic) Information -- 4. Dialectics of Disorder: Normalization and Pathology as Process -- 5. After the Gene. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc |
Publisher's description: The idea of the gene has been a central organizing theme in contemporary biology, and the Human Genome project and biotechnological advances have put the gene in the media spotlight. In this book Lenny Moss reconstructs the history of the gene concept, placing it in the context of the perennial interplay between theories of preformationism and theories of epigenesis. He finds that there are not one, but two, fundamental -- and fundamentally different -- senses of "the gene" in scientific use -- one the heir to preformationism and the other the heir to epigenesis. "Gene-P", the preformationist gene concept, serves as an instrumental predictor of phenotypic outcomes, while "Gene-D", the gene of epigenesis, is a developmental resource that specifies possible amino acid sequences for proteins. Moss argues that the popular idea that genes constitute blueprints for organisms is the result of an unwarranted conflation of these independently valid senses of the gene, and he analyzes the rhetorical basis of this conflation. In the heart of the book, Moss uses the Gene-D/Gene-P distinction to examine the real basis of biological order and of the pathological loss of order in cancer. He provides a detailed analysis of the "order-from-order" role of cell membranes and compartmentalization and considers dynamic approaches to biological order such as that of Stuart Kauffman. He reviews the history of cancer research with an emphasis on the oncogene and tumor suppressor gene models and shows how these gene-centered strategies point back to the significance of higher level, multi-cellular organizational fields in the onset and progression of cancer. Finally, Moss draws on the findings of the Human Genome Project, biological modularity, and the growing interest in resynthesyzing theories of evolution and development to look beyond the "century of the gene" toward a rebirth of biological understanding. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Genetics |
| General subdivision |
Philosophy. |
| 9 (RLIN) |
32052 |
| 650 12 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Genetics. |
| 9 (RLIN) |
32053 |
| 650 22 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Philosophy. |
| 9 (RLIN) |
20203 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE |
|---|
| Uniform title |
Basic bioethics. |
| 9 (RLIN) |
32054 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
Library of Congress Classification |
| Item type |
Circulation |
