000			03199cam a2200313Ia 4500
001			435911966
003			OCoLC
005			20201027112407.0
006			m d
008			090905s2009 nyumb sb a001 0 eng d
020			_a9780816066810
040			_aAEA _cAEA _dAEA _erda
050	1	4	_aQH 442 _b.H664 2009
100	1		_aHodge, Russ, _d1961- _915044
245	1	0	_aGenetic engineering _bmanipulating the mechanisms of life _cRuss Hodge ; foreword by Nadia Rosenthal.
260			_aNew York : _bFacts On File, _c[2009]
264			_aNew York : _bFacts On File, _c[2009]
265			_aGBS
300			_axx, 219 pages : _billustrations (some color), color map ; _c24 cm.
336			_atext _btxt _2rdacontent
337			_aunmediated _bn _2rdamedia
338			_avolume _bnc _2rdacarrier
490			_aGenetics & evolution.
504			_aIncludes bibliographical references (p. 198-205) and index.
505	0		_aFrom breeding to a science of heredity -- The origins of domestic plants and animals -- The rise of agriculture and domestication -- Early ideas of inheritance -- The girl who gave birth to rabbits -- Heredity and the theory of evolution -- Gregor Mendel discovers the laws of heredity -- Classical genetics (1900-1950) -- Cell theory and the discovery of chromosomes -- The rediscovery of Mendel's work -- Chromosomes and heredity -- The debate over natural selection -- Sex and the X-Y chromosomes -- Fruit flies and the birth of the modern laboratory -- Gene maps -- Chromosome puzzles -- Maize and "jumping genes" -- "One gene makes one enzyme" -- Molecular genetics: what genes are and how they work (1950-1970) -- Physics stimulates new ways of thinking about genes -- Genes are made of DNA -- The double helix -- RNA is the messenger -- The architecture of genes -- On-off switches for genes -- The flow of information from gene to protein in complex organisms -- The rise of genetic engineering (1970-1990) -- Recombinant DNA -- Molecular cloning and using bacteria as drug factories -- "Natural" genetic engineering -- DNA sequencing -- The polymerase chain reaction (PCR) -- Making and marketing genetically modified plants and animals for food -- Knockouts, knock ins, and other methods to study gene functions -- Beatrice Mintz: a pioneer of mouse genetics -- Transgenic animals and models of human disease -- DNA fingerprinting -- Genetic engineering in the age of genomes -- The complexity of genomes -- Introns and alternative splicing -- Noncoding RNAs -- Quality control: how cells detect defective genes -- RNA knockouts -- Molecular machines -- Conditional mutagenesis -- Other methods of controlling the output of genes -- Molecular medicine and gene therapies -- DNA vaccines and T-cell therapies -- Personalized medicine in the genome age -- Ethics and genetic engineering -- Reproductive cloning -- Therapeutic cloning and experiments with human cells -- Genetic testing and concerns about eugenics -- GM foods and the rise of environmental movements -- Owning genes, genomes, and living beings -- A look farther ahead.
650		0	_aGenetic engineering _xPopular works. _915045
830		0	_aGenetics and evolution. _915046
942			_2lcc _cREF
999			_c3981 _d3981