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_d8305
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005 20190111112718.0
008 150610t20162016njua b 001 0 eng c
010 _a 2015020801
020 _a9781118771600
040 _erda
050 0 0 _aRS 403
_b.Sm18 2016
245 0 0 _aSmall molecule medicinal chemistry :
_bstrategies and technologies /
_cedited by Werngard Czechtizky, Peter Hamley.
260 _aHoboken, New Jersey :
_bJohn Wiley & Sons, Inc.,
_c[2016].
264 1 _aHoboken, New Jersey :
_bJohn Wiley & Sons, Inc.,
_c[2016].
300 _axiv, 509 pages :
_billustrations (some color) ;
_c24 cm.
336 _atext
_2rdacontent
337 _aunmediated
_2rdamedia
338 _avolume
_2rdacarrier
504 _aIncludes bibliographical references and index.
505 0 _aElements for the development of strategies for compound library enhancement / Edgar Jacoby -- The European lead factory / Christopher Kallus, Jörg Hüser, Philip S. Jones, Adam Nelson -- Access to compound collections : new business models for compound acquisition and sharing / Peter ten Holte -- New advances in diversity-oriented synthesis / Warren R. J. D. Galloway, Jamie E. Stokes, David R. Spring -- Solid-phase combinatorial chemistry : ready for a revival? / Marcel Patek, Martin Smrcina, Eric Wegrzyniak, Victor Nikolaev, Andres Mariscal -- Recent advances in multicomponent reaction chemistry : applications in small molecule drug discovery / Christopher Hulme, Muhammad Ayaz, Guillermo Martinez-Ariza, Federico Medda, Arthur Shaw -- Computational techniques to support hit triage / Douglas B. Kitchen, Hélène Y. Decornez -- Fragment-based drug discovery / Jean-Paul Renaud, Thomas Neumann and Luc Van Hijfte -- Virtual screening / Karl-Heinz Baringhaus, Gerhard Hessler -- Phenotypic screening / Michelle Palmer -- Advances in the understanding of drug properties in medicinal chemistry / Peter Hamley, Patrick Jimonet -- Recent developments in automated solution phase library production / Thomas C. Maier, Werngard Czechtizky -- Adme profiling : an introduction for the medicinal chemist / Katharina Mertsch, Martin Will, Werngard Czechtizky, Niels Griesang, Alexander Marker, Jacob Olsen -- The role of natural products in drug discovery : examples of marketed drugs / Lars Ole Haustedt and Karsten Siems -- Peptidomimetics of a-helical and b-strand protein binding epitopes / Nina Bionda, Rudi Fasan -- In vivo imaging of drug action / Oliver Plettenburg, Matthias Löhn.
650 0 _aPharmaceutical chemistry.
_928486
650 0 _aDrug development.
_928487
700 1 _aCzechtizky, Werngard,
_eeditor.
_928488
700 1 _aHamley, Peter,
_eeditor.
_928489
942 _2lcc
_cGS
984 _a066740
_bmqb